Erratum to: Is aclidinium alone or combined with a LABA a rational choice for symptomatic COPD patients?

نویسندگان

  • F. Blasi
  • G. W. Canonica
  • M. Miravitlles
چکیده

Author details Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Cardio-thoracic unit and Cystic Fibrosis Adult Center Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano, Milan, Italy. Department of Biomedical Science, Personalized Medicine Clinic: Asthma & Allergy Humanitas Clinical and Research Center, Humanitas University – Rozzano (Milano), Milan, Italy. Pneumology Department, Hospital Universitari Vall d’Hebron, Barcelona, Spain.

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Is aclidinium alone or combined with a LABA a rational choice for symptomatic COPD patients?

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The current guidelines on chronic obstructive pulmonary disease (COPD) recommend the prominent use of bronchodilators, including long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists (LAMAs), while inhaled corticosteroids are recommended only in patients with severe disease or frequent exacerbations. LABA-LAMA combinations are indicated when single bronchodilators are insuffici...

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BACKGROUND Patients with chronic obstructive pulmonary disease (COPD) experience respiratory symptoms, which impair quality of life. This pooled analysis of two Phase III studies assessed the impact of aclidinium/formoterol on patients with COPD categorized by symptom status. METHODS Data were pooled from two 24-week, randomized, placebo-controlled studies of twice-daily aclidinium/formoterol...

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Improvement in 24-hour bronchodilation and symptom control with aclidinium bromide versus tiotropium and placebo in symptomatic patients with COPD: post hoc analysis of a Phase IIIb study

BACKGROUND A previous Phase IIIb study (NCT01462929) in patients with moderate to severe COPD demonstrated that 6 weeks of treatment with aclidinium led to improvements in 24-hour bronchodilation comparable to those with tiotropium, and improvement of symptoms versus placebo. This post hoc analysis was performed to assess the effect of treatment in the symptomatic patient group participating in...

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The impact of dual bronchodilation on cardiovascular serious adverse events and mortality in COPD: a quantitative synthesis

Objective Long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) are burdened by the potential risk of inducing cardiovascular serious adverse events (SAEs) in COPD patients. Since the risk of combining a LABA with a LAMA could be greater, we have carried out a quantitative synthesis to investigate the cardiovascular safety profile of LABA/LAMA fixed-dose combinations (F...

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عنوان ژورنال:

دوره 18  شماره 

صفحات  -

تاریخ انتشار 2017